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Technology
Lang AB, Schuerch U. Pilot-scale suspension culture of hybridomas - an overview. In: Doyle A, Griffiths J, editors. Cell and Tissue culture: Laboratory Procedures in Biotechnology. John Wiley & Sons Ltd., 1998: 235-245.
Lang AB, Bruderer U. Influence of somatic cell hybridization and human serum on the generation and stability of human hybridomas. Hybridoma 1992; 11(1):99-106.
Lang AB, Schurch U, Zimmermann F, Bruderer U. Selective generation of antigen-specific human hybridomas optimised for large scale growth in serum-free medium. J Immunol Methods 1992; 154(1):21-26.
Schurch U, Cryz SJ, Lang AB. Scale-up and optimization of culture conditions of a human heterohybridoma producing serotype-specific antibodies to Pseudomonas aeruginosa. Appl Microbiol Biotechnol 1992; 37(4):446-450.
Lang AB, Schuerch U, Cryz SJ. Optimization of growth and secretion of human monoclonal antibodies by hybridomas cultured in serum-free media. Hybridoma 1991; 10(3):401-409.
Lang AB, Furer E, Senyk G, Larrick JW, Cryz SJ. Systematic generation of antigen specific human monoclonal antibodies with therapeutical activities using active immunization. Hum Antibod Hybridomas 1990; 1(2):96-103.
Infectious Diseases
Lang AB, Horn MP, Imboden MA, Zuercher AW. Prophylaxis and therapy of Pseudomonas aeruginosa infection in cystic fibrosis and immunocompromised patients. Vaccine 2004; 22:S44-S48.
Vogel M, Zhang LL, Rudolf MP, Curcio-Vonlanthen V, Miescher S, Stadler BM.. Cross reactive anti-tetanus and anti-mellitin Fab fragments by phage display after tetanus toxoid immunisation. Hum Antibod Hybridomas 1996; 7 (1):11-20.
Lang AB, Vogel M, Viret JF, Stadler BM. Polyclonal preparations of anti-tetanus toxoid antibodies derived from a combinatorial library confer protection. Nature/Biotechnology 1995; 13(7):683-685.
Lang AB, Furer E, Cryz SJ. Feasibility of prophylaxis and therapy against gram-negative infections by human monoclonal antibodies. FEMS Immunol Med Microbiol 1993; 7(1):9-13.
Lang AB, Cryz SJ, Schurch U, Ganss MT, Bruderer U. Immunotherapy with human monoclonal antibodies. Fragment A specificity of polyclonal and monoclonal antibodies is crucial for full protection against tetanus toxin. J Immunol 1993; 151(1):466-472.
Bruderer U, Deusinger M, Schurch U, Lang AB. Affinities of endotoxin-specific human monoclonal antibodies, their polyclonal counterparts and murine monoclonal antibodies. Res Immunol 1993; 144(9):659-665.
Lang AB, Bruderer U, Senyk G, Pitt TL, Larrick JW, Cryz SJ. Human monoclonal antibodies specific for capsular polysaccharides of Klebsiella recognize clusters of multiple serotypes. J Immunol 1991; 146(9):3160-3164.
Lang AB, Bruderer U, Furer E, Larrick JW, Cryz SJ. Immunoprotective capacities of human and murine monoclonal antibodies recognizing serotype-specific and common determinants of gram-negative bacteria. In: Therapeutic Monoclonal Antibodies. Stockton Press, NY, 1990: 223-234.
Lang AB, Furer E, Larrick JW, Cryz SJ. Isolation and characterisation of a human monoclonal antibody that recognises epitopes shared by Pseudomonas aeruginosa immunotype 1, 3, 4, and 6 lipopolysaccharides. Infect Immun 1989; 57(12):3851-3855.
Others
Rudolf MP, Zürcher AW, Nechansky A, Ruf C, Vogel M, Miescher SM, Stadler BM, Kricek F.. Molecular basis for non-anaphylactogenicity of a monoclonal Anti-IgE antibody. J Immunol 2000; 165(2):813-819
Zürcher AW, Miescher SM, Vogel M, Rudolf MP, Stadler MB, Stadler BM. Oral anti-immunoglobulin E immunization with epitope-displaying phage. Eur J Immunol 2000; 30(1):128-135.
Thurnheer MC, Zürcher AW, Miescher SM, Rudolf MP, Vogel M, Stadler BM. Molecular mimicry of the unidentified antigen of myeloma antibody IgE-ND. Eur J Immunol 1999; 29(9):2676-83.
Pachlopnik JM, Stampfli MR, Rudolf MP, Aebischer I, Kricek F, Miescher S, Stadler BM. Antigen interaction and heat inactivation expose new epitopes on human IgE. Int Arch Allergy Immunol 1998; 117(4):231-8.
Rudolf MP, Vogel M, Kricek F, Ruf C, Zürcher A W, Reuschel R, Auer M, Miescher S, Stadler BM. Epitope specific antibody response to IgE by mimotope immunization. J Immunol 1998; 160 (7): 3315-3321.
Fehr T, Bachmann MF, Bucher E, Kalinke U, Di Padova FE, Lang AB, Hengartner H, Zinkernagel RM. Role of repetitive antigen patterns for induction of antibodies against antibodies. J Exp Med 1997; 185(10):1785-1792.
Stadler BM, Stampfli M, Vogel M, Rudolf MP, Zürcher AW, Miescher S. Natural and recombinant anti-IgE autoantibodies. Adv Exp Med Biol 1996; 409: 411-416.
Rudolf MP, Furukawa K, Miescher S, Vogel M, Kricek F, Stadler BM. Effect of anti-IgE antibodies on Fc?RI bound IgE. J Immunol 1996; 157(12), 5646-5652.
Stämpfli MR, Rudolf MP, Miescher S, Pachlopnik JM, Stadler BM. Antigen specific inhibition of IgE binding to the high affinity receptor. J. Immunol. 1995; 155 (6): 2948-2954.
Stadler BM, Stämpfli MR, Miescher S, Rudolf MP, Vogel M. Cloning of human anti-IgE autoantibodies and their role in the regulation of IgE synthesis. Int Arch Allergy Immunol, 1995; 107 (1-3): 48-50.
Zurcher AW, Lang AB, Aebischer I, Miescher S, Stadler BM. IgE-producing hybridomas established after B-cell culture in the CD40 system. Immunol Lett 1995; 46(1-2):49-57.
Pluschke G, Lang AB. Möglichkeiten der therapeutischen Anwendung von monoklonalen Antikörpern. Die Medizinische Welt 1995; 46:188-198.
Schneider T, Lang AB, Carballido JM, Santamaria Babi LF, Dudler T, Kagi MK, Blaser K, Suter M. Human monoclonal or polyclonal antibodies recognize predominantly discontinuous epitopes on bee venom phospholipase A2. J Allergy Clin Immunol 1994; 94(1):61-70.
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